angiotensin ii type 1 receptor การใช้

• SND1 promotes migration and invasion via angiotensin II type 1 receptor and TGF? signaling.
• As with all angiotensin II type 1 receptor ( AT 1 ) antagonists, losartan is indicated for the treatment of hypertension.
• Anti-PAF drugs are used to block angiotensin II type 1 receptors to lower in the risk of atrial fibrillation in individuals with paroxysmal fibrillation.
• Angiotensin II receptor antagonists that have existed in the pharmaceutical market have had higher affinities for angiotensin II type 1 receptors ( ATR ) over type 2 receptors.
• EMA401 is the first drug on the market that targets angiotensin II type 2 receptors ( ATR ) with high affinity but has a low affinity for angiotensin II type 1 receptors.
• These investigations led to the discovery of two subtypes of membrane bound G protein-coupled angiotensin receptors within the renin-angiotensin system with vastly different functions : angiotensin II type 1 receptors ( ATR ) and angiotensin II type 2 receptors ( ATR ).